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Nespo (darbepoetin alfa) - B03XA02

Updated on site: 08-Oct-2017

Naziv lijekaNespo
ATK šifraB03XA02
Tvardarbepoetin alfa
ProizvođačDompé Biotec S.p.A.

Sadržaj članka

Nespo is a solution for injection in a vial, a pre-filled syringe or a pre-filled pen. It contains the active substance darbepoetin alfa. Nespo exists in various strengths, from 10 to 500 micrograms per millilitre. See the Package Leaflet for full details.

Nespo is used to treat anaemia (fewer red blood cells in the blood than normal) in two groups of

the body does not produce enough of the natural hormone erythropoietin,

• adult patients with certain types of cancer who are receiving chemotherapy (the medicines used to treat cancer), when the chemotherapy stops the bone marrow producing enough blood cells. The types of cancer where Nespo can be used are ‘non-myeloid’ (do not affect the bone marrow).

The medicine can only be obtained with a prescription.

NespoMedicinaltreatment should be initiated by a doctor who has experience in treating either of the two types of anaemia mentioned above. Nespo is injected intravenously (into a vein) or subcutaneously (under

the skin). The dose used depends on why Nespo is used, varying from 0.45 micrograms per kilogram every week (or 0.75 micrograms/kg every other week) in adults and children with kidney failure aged 11 years or older, to 6.75 micrograms/kg every three weeks in cancer patients. Lower doses may be necessary for children with kidney failure aged 10 years or below. In all cases the doses are adjusted to obtain haemoglobin levels that remain within the recommended range. Haemoglobin is the protein in red blood cells that carries oxygen around the body.

Doses and dose frequency (how often Nespo is given) are adjusted depending on the response. Nespo is supplied ready for use in a pre-filled syringe or pre-filled pen, which can be used by the patient or their carer. See the Package Leaflet for full instructions for use.

How does Nespo work?

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